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Description
Adipose tissue, particularly visceral fat, is metabolically active and secretes pro-inflammatory adipokines

Additionally, retatrutide lowered blood glucose and insulin levels, suggesting that retatrutide enhanced insulin sensitivity

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Beginning with the EMPA-REG OUTCOME trial in 2015, multiple glucose-lowering therapies have demonstrated a reduction in cardiovascular outcomes in people both with and without T2D
It has a shorter plasma halflife compared to other DPP4is and is typically dosed twice daily [103, 104]
