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Description
Insulin levels control fat storage and once the insulin levels are high, the body is in fat storage mode

The simplest way to understand the difference is this: tirzepatide is a dual agonist, while retatrutide is a triple agonist

2011 May;19(5):985-93

The addition of glucagon receptor activation introduces another variable that could theoretically affect fluid balance and salivary function, though specific data on retatrutide versus tirzepatide for dry mouth are not yet available
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