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Pharmacologically , semaglutide begins to exert effects on blood glucose regulation within the first few days of treatment, as it starts to influence insulin and glucagon secretion

But if you get side effects that dont go away or make it hard to eat enough or exercise, tell the doctor who prescribed your GLP-1

That approaches what people can lose with weight-loss surgery

2 The addition of semaglutide to the Food and Drug Administration (FDA) shortage list from 2022 to February 2025, and tirzepatide to the same list from 2022 to December 2024, gave compounding pharmacies permission by the FDA to produce exact duplicates to ensure continuity of treatment until production met demand