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Description
When you take Wegovy, it activates GLP-1 receptors in the brain

But it comes with caveats

doi: 10.1016/j.cppeds.2020.100871

Cell-based experiments also demonstrate receptor-dependent signaling changes when Retatrutide interacts with GLP-1R, GIPR, or GCGR expressing cells

Cardiovascular safety may be assessed either before or after authorisation, depending on the indication and the risk profile of the medicine this is determined on a case-by-case basis and is not universally required pre-authorisation, particularly for obesity indications
