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Journal reference: Wong CK, Drucker DJ (2025)

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If you take insulin or sulfonylureas along with tirzepatide, your healthcare provider may need to reduce these doses to prevent hypoglycemia

Animal studies demonstrated that the distribution of these receptors is particularly important for oestrogens ability to modulate its effects on fat distribution [16,39,40]

The only difference is the FDA-approved indication: Zepbound for chronic weight management, Mounjaro for type 2 diabetes