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However, orforglipron patients lost around twice as much, at between 4.7% and 7.9% of their weight
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2023), which is accompanied by greater symptom severity, reduced exercise capacity, more adverse hemodynamics, and a greater risk of hospitalization for HF than those living with HFpEF without obesity (Borlaug et al
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The DPP-4 inhibitors are well tolerated and are considered weight-neutral
