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F., & Bindra, R

Interview with Semaglutide User #1: Sarah's Journey to a Healthier Self Sarah, a mother of two in her mid-30s, had struggled with her weight for years

Safety, Risks, and Provider Oversight What to know: Lower dose is not lower risk: FDA boxed warnings and contraindications for semaglutide apply at any dose, and adverse events including nausea, gallbladder issues, and rare pancreatitis can still occur, which is why a licensed-provider evaluation and ongoing monitoring are required

DOI: 10.3390/ijms20143435 [Google Scholar] Sato T, Shimizu T, Fujita H, Imai Y, Drucker DJ, Seino Y, et al

For polyendocrine metabolic ovarian syndrome (PMOS), characterized by insulin resistance and metabolic dysfunction, a 2024 meta-analysis found that GLP-1 receptor agonists reduce BMI, triglycerides, waist circumference and total testosterone in affected women, and international PMOS guidelines recognize them as candidate therapy for overweight and obese patients, but there are not ongoing Phase 3 trials