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10 Additionally, not all OSA patients are obese and therefore wouldnt benefit from GLP-1s

By adopting a holistic approach, you can maximize the benefits of these treatments and set yourself up for long-term success
One often-cited study compared oral berberine supplementation to metformin in a small trial of participants with type 2 diabetes
In this group, 963 participants using GLP-1RAs developed depression, and 1,075 participants using DPP4is developed depression
Some clinical trials suggest combination therapy with both SGLT2 inhibitors and GLP-1 agonists may provide up to 27% total weight loss, though this approach requires careful medical supervision