do you lose weight faster with semaglutide or tirzepatide vs Tirzepatide, which is better for you? Semaglutide vs Tirzepatide- Start your
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Elevated blood pressure
Tirzepatide helped participants lose an average of 20.9% of their body weight

Some research suggests that individuals who have lost significant weight may experience lower metabolic rates than predicted for their new body size, though this varies considerably between individuals
9 Notably, these agents have also led to a significant decrease in major cardiac events, regardless of their effect on blood glucose, indicating a dual benefit for both cardiac health and diabetes management

This would explain their nausea/emesis side effects and also support the previous experimental findings that GLP1 receptor agonists in the arcuate nucleus, rather than the area postrema, are most important for the intakesuppressive effects of these agonists (Secher et al., 2014)
