retatrutide clinical trials phase 2 Trial of for Obesity Retatrutide Commercial Availability Timeline: Key
Description
Partnerships with telehealth platforms, patient acquisition vendors and performance marketing agencies require clear governance and oversight
Very limited safety database (125 patients, 13 weeks)
Nonetheless, chylomicrons have been reported to be powerful GPR40-Gq activators and GLP-1 secretagogues, acting from the basolateral side of the intestinal mucosa (264)
doi: 10.1016/S0140-6736(19)30772-X
Hence, the action of dual GLP-1R/GcgR agonists likely results from a combination of central and peripheral mechanisms, at multiple target tissues
