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And it can cross the blood-rain barrier, reduce inflammation and oxidative stress, and protect synapses and neurons, showing neuroprotective effects in animal models of AD and PD (Hong et al., 2024)

More recent semaglutide data suggest improvements in sperm morphology and testosterone while preserving normal gonadotropin signaling. Philip Werthman, MD One of the most important clinical distinctions is that GLP-1 therapies appear fundamentally different from testosterone replacement therapy for men who wish to preserve fertility, he noted

and Bart C

While we dont have specific studies looking at the use of expired semaglutide, its generally accepted that expired medications become less effective over time

An atlas of genetic correlations across human diseases and traits
