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Healthcare experts increasingly recognize sleep quality and stress management as important components of successful GLP-1 treatment

On a cellular level, the polarization of macrophages has been stimulated by this molecule, shifting them from the inflammatory M1 phenotype to the anti-inflammatory M2 phenotype, which plays a vital role in tissue regeneration as well in reducing inflammation, as they produce cytokines like IL-10 and TGF-[5]

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Despite these potential anti-inflammatory mechanisms, molecular imaging studies have yielded discrepant results about whether GLP-1 RAs can attenuate vascular wall inflammation

ClinicalTrials.gov (2018)