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Theres also a major caveat here: GLP-1s are considered a pregnancy category C medication

Orforglipron was granted one of these The FDA has stated that the initiative is intended to pioneer new ways of bringing these cures and meaningful treatments to the market faster, particularly in areas of high public health need

In fact, the GLP-1 RAs can be categorised structurally into two major groups (see Table 1

References: PMC8315201, PMC11273815, PMC3569688, PMC9518699, PMC11853085

Persistence and adherence rates similar to those seen in our study were reported in another US observational study that used PS-matched cohorts to compare outcomes in patients with T2D initiating treatment with once-weekly dulaglutide or with once-daily liraglutide [23]