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Most importantly, flexibility matters

June 2024: Structure Therapeutics reported positive Phase IIa obesity data for GSBR-1290, an oral non-peptide small-molecule GLP-1 receptor agonist, achieving 6.2% placebo-adjusted mean weight loss at 12 weeks

Preclinical studies have validated the therapeutic potential of these compounds for the treatment of obesity and diabetes

But there is a difference between starving and having sustainable appetite control

Whether the combination changes the risk profile is unstudied
