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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Tao Y, Ge G, Wang Q, Wang W, Zhang W, Bai J, et al

Survodutida es un agonista dual GLP-1R/GCGR en una proporcin de 8:1 que tambin demostr eficacia en un ensayo de fase 2 de 48 semanas realizado en 293 adultos (IMC 35,816,41kg/m2, DM2 en 39%) con esteatohepatitis y fibrosis F1 a F3

Data Availability All data supporting the findings of this study are available within the article and its Supplementary Information file, or are available from the authors upon reasonable request

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Systemic administration of fluorescently labeled tirzepatide in rodents resulted in labeling of the median eminence, area postrema, and other circumventricular organs in the brain, indicating one route of how tirzepatide may access parts of the brain to exert its effects [67]
