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1) GLP-1s for type 2 diabetes The hormone GLP-1 binds to GLP-1 receptors in the pancreas to increase insulin release after a meal

Its likely that GLP-1 RAs (or their combinations) will be part of a future MASH therapy regimen, given weight loss is the cornerstone treatment and GLP-1 causes weight loss plus some direct hepatic fat reduction

Nat Rev Gastroenterol Hepatol

The semaglutide appetite suppression timeline typically shows effects within the first one to two weeks
