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Ethics declarations Competing Interests All authors, with the exception of A.J.C., A.K., D.F., E.R., K.D., L.J

The results of the studies, funded by Eli Lilly, were presented at the American Diabetes Association conference in Orlando and published in the New England Journal of Medicine
Breast Cancer Prevention The findings demonstrate that GLP-1 users had nearly 30% lower odds of being diagnosed with breast cancer
The first dedicated kidney outcome trial with the GLP-1 receptor agonist semaglutide was published more recently

This variability likely reflects heterogeneity in the biological drivers of obesity across individuals, suggesting opportunity for precision medicine approaches that match patients to optimal therapeutic mechanisms
