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The microbiota plays a critical role in intestinal immunity, and dysbiosis may be involved in the pathogenesis of obesity and metabolic syndrome by inducing low-grade inflammation in remote organs such as the liver or adipose tissue [156]

Characteristics of GLP-1 and exendins action upon glucose transport and metabolism in type 2 diabetic rat skeletal muscle

GLP-1 also inhibits gastric emptying [7], which contributes to reducing postprandial glucose excursions

[DOI] [PubMed] [Google Scholar] 131.Loomba R, Hartman ML, Lawitz EJ, et al

From an epidemiological perspective, T2DM is a highly prevalent disease worldwide, affecting more than 500 million individuals, with a reported prevalence of approximately 14% among elderly populations in China 2 , 33
