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They can increase hepatic insulin sensitivity (i.e., increase hepatocytes insulin response) by decreasing steatosis and improving liver histology
Lundgren JR, Janus C, Jensen SB, Juhl CR, Olsen LM, Christensen RM, et al
BMI 27 with weight-related conditions, such as: Type 2 diabetes or prediabetes Hypertension High cholesterol Sleep apnea Fatty liver disease (NAFLD) PCOS Insulin resistance Patients in this range may be candidates because GLP-1 medications act on pathways related to blood sugar, appetite, and metabolic regulation
Discuss choice with your provider based on goals and tolerability
More than 7 years of hindsight: revisiting the FDAs 2008 guidance on cardiovascular outcomes trials for type 2 diabetes medications
