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Patients should understand that expected weight loss varies by medication (approximately 5-10% with liraglutide, 10-15% with semaglutide, and potentially higher with tirzepatide), though responses in post-bariatric patients may differ from those in primary obesity treatment

These GLP-1 drugs primarily work by enhancing satiety, slowing gastric emptying, and modulating insulin secretion

Additionally, there is a boxed warning regarding thyroid C-cell tumors observed in rodent studies

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Social media influencers are touting a new option for popular weight loss drugs: GLP-1 patches, they say, are just as powerful as Ozempic for shedding pounds without the discomfort of needles or the hassle of getting a prescription