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Beta-hydroxybutyrate, a marker of fatty acid oxidation, increased by 78% to 181%, confirming that retatrutide drives substantial fat burning at the cellular level

M.DiakogiannakiE.et al (2012)
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In Phase 2 trials, it showed up to 24% weight loss , with a higher side effect rate than the approved options

Retatrutide Side Effects and Safety Profile: What to Expect In ongoing global studies focused on advanced therapies for weight management, the safety and tolerability profile of investigational agents like retatrutide is a primary endpoint