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3.2.1 Literature quality assessment As shown in Table 2, all 13 studies [1123] reported random sequence generation and were rated as low risk. Three studies [11,12,20] had unclear allocation concealment and were marked as some concerns. Twelve trials [1223] were double-blinded and rated as low risk, while one study [11] had some concerns regarding blinding

Clinical trial(s) The global, double-blind, placebo-controlled Phase 3 SCORPIO-PEP trial (NCT05897541), conducted between June 2023 and September 2024, evaluated ensitrelvir for the prevention of COVID-19 following exposure to an infected individual

By contrast, to the best of our knowledge, there is currently no direct experimental evidence exploring the effects of dulaglutide or semaglutide on erectile function

Adolescent onset schizophrenia has also long been theorized to be related to altered grey matter development secondary to marijuana[116]