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Binary clinical outcomes, including acute kidney injury, severe hypoglycemia, adverse events leading to treatment discontinuation, and cardiovascular events, were summarized descriptively without formal hypothesis testing, given the absence of a comparator group and limited statistical power

While additional research is required to evaluate the drug's side effects and those of similar GLP-1R agonists, these findings form the basis for developing the next generation of anti-weight-gain therapeutics

GLP-1 medications reduce progression from prediabetes to diabetes by 72% compared to control groups 6

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Yerba Mat Does Not Directly Stimulate GLP-1 Production in L-Cells To assess the direct effects of YM on GLP-1 secretion, GLUTag L-cells were incubated with YM for 0, 12, and 24 h, and GLP-1 levels in the supernatant were quantified