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1 The discovery of GLP-1 The journey began with Habener and Mojsovs identification of the physiological roles of GLP-1, a hormone initially discovered as an incretin, which is released by the gut (Drucker et al 1986) (Fig

95% CI, 0.89-2.53)

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It does not cause dependence, does not interact with GLP-1 receptor agonists, and works through an osmotic mechanism rather than stimulating the colon directly

Repurposing GLP-1 receptor agonists for alcohol use disorder: a systematic review and meta-analysis