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Pharmacokinetic comparisons indicate that intranasal delivery of exenatide or dulaglutide leads to preferential accumulation in the hippocampus and neocortex within 30 min, with higher regional exposure than intravenous administration, even in amyloid precursor protein/presenilin 1 mice ( APP /PS1) transgenic mice [278]
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Ther Adv Endocrinol Metab (2021) 12:204201882198923
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival
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