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Background The global prevalence of obesity has soared to a concerning height in the past few decades

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Liver-directed therapies with efficacy in metabolic dysfunction-associated steatotic liver disease (MASLD), including incretin-based agents, fibroblast growth factor 21 analogs, peroxisome proliferator-activated receptor agonists, and thyroid hormone receptor beta agonists, may benefit selected MetALD patients

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Tirzepatide is a dual GIP and GLP-1 receptor agonist, making it one of the most powerful weight loss medications available