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Hussain A et al

Approximately 60% of patients in clinical practice choose chronic treatment specifically to avoid regain

The SELECT trial demonstrated a 20% reduction in major adverse cardiovascular events in 17,604 adults with preexisting cardiovascular disease, overweight or obesity, without diabetes [1] [2]

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A different randomized trial of exenatide (a GLP-1RA sold as Byetta or Bydureon) in Parkinsons patients also showed benefit, and the effects persisted even after a washout period following treatment
