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Patients who develop a lump or swelling in the neck, hoarseness, difficulty swallowing, or shortness of breath should contact a provider immediately

Individual variation is significant, and this combination should only be considered with guidance from a knowledgeable provider

If that trial or others find that GLP-1s do reduce breast cancer risks, it could be a huge win for women at high risk of the disease

Orforglipron could also be set for FDA submission for type 2 diabetes management in 2026

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