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In patients with obesity (mean age 51.3 years, 65.6% women), semaglutide compared with non-GLP-1RA anti-obesity medications was associated with lower risk for incident CUD in patients with no prior history CUD (HR: 0.56, 95% CI: 0.420.75), and recurrent CUD diagnosis in patients with a prior history CUD (HR: 0.62, 95% CI: 0.460.84)

Embrace the Chill (The Energy Burn) This one may feel uncomfortable, but short bursts of cold exposure (like a 30-second cold shower finish) dont just wake you up, they stimulate your Brown Fat (BAT).Brown fats job is to burn calories for heat, and its activation improves overall metabolic health and insulin sensitivity.While the connection is indirect, research suggests that this major metabolic wake-up call creates an environment that supports the healthy function and release of critical signalling hormones like GLP-1, helping to optimise your body's energy balance

As of early 2026, several potent single, dual, and triple incretin receptor agonists are in Phase 2/3 trials for MASH including : Survodutide : A dual glucagon (GCGR)/GLP-1 receptor agonist that has shown significant MASH resolution in Phase 2 trials