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Total RNA was extracted using the TaqMan Reverse Transcription kit (Thermo Fisher Scientific)

Participants taking bofanglutide experienced weight loss and improvements in various cardiometabolic risk factors

Given its unique pharmacological design, retatrutide influences appetite reduction, delayed gastric emptying, glucose regulation, and increased energy expenditure

Obesity, currently defined as a body mass index (BMI) of 30 kg/m 2 or greater, affects 800 million people worldwide [1]
