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Nauck MA, Quast DR, Wefers J, Meier JJ (2021) GLP-1 receptor agonists in the treatment of type 2 diabetes - state-of-the-art

The short answer is that we do not know for sure so it is really important to discuss the data

Zhao, H

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Weight returns because GLP-1 medications suppress appetite and improve insulin sensitivity while active, but do not change the underlying metabolic, hormonal, and inflammatory drivers of weight gain
