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Researchers still think patients should receive an injectable version of semaglutide when possible, but new data out of ACC.25 confirm that an oral formulation of the drug is associated with significant benefits.

In a crossover trial evaluating semaglutide versus placebo as an add-on to automated insulin delivery therapy in adults with type 1 diabetes, the use of semaglutide was associated with an increased percentage of time spent within the target glucose range, along with reduced insulin requirements.

Allergic reactions to GLP-1 receptor agonists typically manifest as injection site reactions, but can progress to serious systemic hypersensitivity including...

Retatrutide is being studied as a broader metabolic approach

Were spending a lot of time, education, and effort to distinguish the two, exec Sylvia Shubert said.