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Approximately 60% of CagriSema-treated participants achieved at least 20% weight loss, and 40.4% achieved at least 25% loss, with some participants losing over 30% of body weight

Because other things fill that gap.

The science of healthy habit change scaled for organizations

[6] Preclinical studies in animal models suggest that GLP-1 receptor activation may: Promote neuroplasticity and neurogenesis (formation of new neurons) in the hippocampus, a region often showing reduced volume in depression Modulate neurotransmitter systems , particularly dopamine and serotonin pathways involved in mood regulation and reward processing Reduce neuroinflammation , which is increasingly recognised as contributing to depressive disorders Enhance brain-derived neurotrophic factor (BDNF) expression, a protein crucial for neuronal health and resilience Metabolic improvements associated with GLP-1 therapy may also contribute indirectly to mood benefits

The landscape around GLP-1 coverage is changing quickly, so its worth rechecking your plan at each renewal.