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Description
Semaglutide inhibits ischemia/reperfusion-induced cardiomyocyte apoptosis through activating PKG/PKC/ERK1/2 pathway

This study showed that once-weekly dulaglutide has noninferiority to once-daily liraglutide in reducing HbA1c with a similar safety profile96)

On one hand, IR leads to abnormal glucose uptake and oxidation, reduced glycogen synthesis, and decreased ability to inhibit lipid metabolism, resulting in glucose metabolism imbalance
E.et al (2017)

OCP, oral contraceptive pill