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Research published in clinical obesity journals demonstrates that weight regain accelerates 6-12 months after treatment cessation, particularly if lifestyle habits haven't been permanently reinforced
Moreover, in humans, sDPP-4 appeared to increase obesity and insulin resistance, but it was not associated with systemic metabolic inflammation (IL-6 or CRP levels), evidencing the complexity of the role of sDPP-4 in the inflammatory processes [64]
