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Bioengineered nanomedicines targeting the intestinal fc receptor achieve the improved glucoregulatory effect of semaglutide in a type 2 diabetic mice model

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Those with active pancreatitis or a history of severe GI motility issues (since these medications slow digestion)

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If there are no GI AEs, then, in the authors clinical experience, uptitration may be performed rapidly, for example, increasing to the next dose after 24 weeks, although the lower end of this range may not be in accordance with the product label and cost may need to be considered when deciding on an uptitration schedule