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New real-world research presented at the AAAAI Annual Meeting suggests that glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may significantly reduce asthma exacerbations in overweight and obese adults without diabetes pointing to a potential new therapeutic strategy for a difficult-to-treat population.

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Introduction This study evaluated the long-term effectiveness of once-weekly subcutaneous semaglutide versus alternative treatment in adults with type 2 diabetes (T2D) in routine clinical practice.Research design and methods The SEmaglutide PRAgmatic (SEPRA) was a 2-year, randomized, open-label, pragmatic clinical trial ( NCT03596450)
