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Recommendation tiers: (i) Strongly Recommended: GLP-1RAs may be used as time-bounded metabolic optimization before OI or ART, aiming to improve metabolic readiness prior to stimulation and pregnancy planning

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The receptor profiles are different (dual versus triple agonist), the potency per milligram is different, and the side effect profiles are different

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However, the framing of this data matters

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Regarding other GLP-1RAs, such as liraglutide and albiglutide, no dose adjustment is necessary in patients with renal impairment, as these drugs are not renally excreted

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Diz-Chaves Y, Herrera-Prez S, Gonzlez-Matas LC, et al

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