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Recommendation tiers: (i) Strongly Recommended: GLP-1RAs may be used as time-bounded metabolic optimization before OI or ART, aiming to improve metabolic readiness prior to stimulation and pregnancy planning

The receptor profiles are different (dual versus triple agonist), the potency per milligram is different, and the side effect profiles are different

However, the framing of this data matters

Regarding other GLP-1RAs, such as liraglutide and albiglutide, no dose adjustment is necessary in patients with renal impairment, as these drugs are not renally excreted

Diz-Chaves Y, Herrera-Prez S, Gonzlez-Matas LC, et al
