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Multiple analyses show that when treatment is stopped, most people regain some or all of the weight they lostsometimes moreand that the cardiometabolic benefits do not persist off-drug

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SSRI Antidepressants: Legal and Safety Concerns SSRIs treat depression and anxiety, but lawsuits and FDA warnings link them to serious risks like suicidality in young people, birth defects and withdrawal symptoms

(1996) 271:R84856

Phase 2b data from the VESPER trials showed competitive weight loss with the potential for once-monthly, titration-free administration
