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[2] [4] Beyond addressing constipation, adequate fibre intake supports the gut microbiome, which may influence metabolic health and weight management outcomes, though research in this area is still emerging

Mood symptoms Animal studies, case reports, and a meta-analysis of RCTs of GLP-1 RAs suggest that these medications might help with depression (Chen X et al, Am J Geriatr Psychiatry 2024;32(1):117127)

She required physical therapy to regain mobility

A BMI of 30 is typically used as a cutoff for obesity, while 25 is used as the cutoff for overweight

Dipeptidyl-peptidase-IV (DPP-4) is an enzyme located on epithelial and endothelial cells, expressed in several tissues throughout the body, including the lungs, liver, kidneys, small intestine, brain, and spinal cord [47,48]