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To prevent the onset of obesity and to improve psychomotor development, it is advisable to start GH therapy as soon as possible, between 3 and 6 months of age, monitoring the glucose profile due to the diabetogenic effect of the GH, and the risk of OSA by polysomnography [13]

Lab integration & longitudinal follow-up (15 pts)

56 In patients with prediabetes, there is a characteristic loss of first phase GSIS that can be restored quickly under conditions of administered GLP-1

However, these results were not statistically significant

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