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Description
TRIM21 promotes tumor growth and gemcitabine resistance in pancreatic cancer by inhibiting EPHX1-mediated arachidonic acid metabolism

Cell Metab (2018) 27:74056
Key Tip : Ask your doctor if you need to change the timing of your medications or use alternative forms like injections

By subsampling the training cohort, these authors showed increased predictive accuracy with increased cohort size, with ~750010,000 individuals optimal for replicable results

About 5% do not respond to or tolerate any GLP-1 medication, meaning they have minimal or no weight loss or must stop treatment due to side effects
