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NIT-1 cells treated with PA+Ex-4 and PA+GW showed enhanced GSIS capacity, increased PPAR expression, decreased UCP2 expression and ADP/ATP ratio, and improved mitochondrial DNA content and mitochondrial membrane potential compared with those treated with PA alone, whereas the opposite results were observed in the PA+GSK group

For anti-obesity GLP-1s, Medicares policy of not covering AOMs means that utilization skews heavily Commercial

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Further research is required to confirm these findings, understand the mechanisms involved, and evaluate their long-term impact on smoking-related outcomes.