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As more people start using them, some are talking about the unexpected side effects, including muscle loss and weakness

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Gynecomastia describes the swelling of breast tissue in males, caused by a decrease in the level of testosterone compared with the level of estrogen.

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After all, people with obesity have more muscle mass than people without obesity (because their bodies carry more weight), so it's normal to lose muscle when you lose weight whether by diet, exercise, medications, or surgery