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All reconstitution actions must be recorded, along with environmental tracking data and user names

Statistical analysis The data were analysed by SPSS IBM Version 23 or GraphPad Prism 7.0 software and expressed as the means SEM

8,129,343 (343) and 8,536,122 (122)

Results showed a significant reduction in Body Mass Index (BMI) over 24 months, with mean differences of 0.36, 1.08, 1.18, and 1.42 at 3, 6, 12, and 24 months, respectively, with 95% CI, and low heterogeneity ( I = 0.0%)

Discuss pregnancy plans with your healthcare provider, as weight loss medications should be discontinued at least 2 months before a planned pregnancy