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That's why a one-size-fits-all approach to managing side effects often falls short

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Topiramate can cause metabolic acidosis which, when occurring during pregnancy, has been associated with decreased fetal growth, decreased fetal oxygenation, fetal death, and may impact the ability of the fetus to tolerate labor

This classification differs from Alfonzos NICE (National Institute for Health and Care Excellence) guideline from the UK, where severe only starts at K = 6.5 mmol/L [9]