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Limited Visibility In a 1:1 matched case-control study performed by Chapman et al., patients getting GLP-1 RAs had significantly lower visibility scores during EGD and were 4.62 times more likely to have retained gastric contents compared to patients not on GLP-1 RAs ( p -value 0.025) [23]

While researchers primarily use GLP-1 antagonists for other medical purposes, they continue to explore their potential in metabolism and weight management

Limited Insurance Coverage:Insurance coverage for weight loss drugs, including GLP-1 agonists, is often inadequate in the GCC region

16 The patterns indicating improvement in headache and visual results, albeit not statistically significant, imply intricate underlying pathophysiological pathways that need additional exploration in prospective therapeutic trials