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This article looks at the scientific evidence and provides recommendations.

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Other combinations of entero-pancreatic hormones including cagrisema (GLP-1/amylin RA) and the triple agonist retatrutide (GLP-1/GIP/glucagon RA) have also progressed to phase 3 trials as obesity treatments and early data suggests that may lead to even greater WL than tirzepatide

Originally developed to help people with type 2 diabetes manage blood sugar, the drug semaglutide, commonly known by the brand names Ozempic or Wegovy, has shown promise for other health issues as well