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Diabetic Retinopathy Complications in Patients with Type 2 Diabetes: Temporary worsening of diabetic retinopathy has been associated with rapid improvement in glucose control

The MHRA update also complements the recent consensus statement from anaesthetic and specialist organisations that provides guidance for how the increased risk can be managed safely in the perioperative period. In early January 2025, the Association of Anaesthetists published a multidisciplinary consensus statement on elective peri-operative management of adults taking GLP-1 and dual GIP/GLP-1 RAs, which advised that patients take GLP-1 or dual GIP/GLP-1 RAs as normal, as well as receive a full risk assessment and peri-operative techniques to mitigate risk of pulmonary aspiration during the peri-operative period

But like all pharmaceuticals, Ozempic (and its weight loss version, Wegovy) is not without risk

In my opinion, the message here isnt that people should avoid these medications for fear of regaining weight

Emerging research suggests that some lean mass decline may actually be considered adaptive, reflecting improved muscle quality and healthier body composition