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However, diabetic individuals should monitor blood glucose more closely when starting creatine, as the combined effect on glucose metabolism could theoretically increase hypoglycemia risk, especially if also taking insulin or sulfonylureas

Older adults may see slightly slower initial response but achieve similar long-term outcomes

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While some users report a mild, clean increase in stamina within the first few days, the profound metabolic shiftssuch as increased endurance, better insulin response, and gradual fat losscompound over weeks of consistent use as mitochondrial efficiency is restored